Remya Rajan
Research Interests:
- Basal ganglia
- Electrophysiology
- Reward and related signaling pathways
- Synaptic plasticity
- Reward pathways
- Neurodevelopmental disorders
My research focuses on how molecular and cellular perturbations shaped by genetic, hormonal, and environmental factors translate into circuit-level dysfunction that increases vulnerability to neurodegenerative and neuropsychiatric diseases. I was trained in medicinal chemistry and neuropharmacology, where I developed and functionally validated subtype-selective NMDA receptor ligands using patch-clamp electrophysiology. This work sparked a sustained interest in how molecular and cellular perturbations scale to dysfunction at the circuit level. To expand my expertise in neural circuit mechanisms, I pursued postdoctoral training in ex vivo electrophysiology and synaptic physiology, focusing on sex-dependent changes in neuronal excitability in disease-relevant circuits. My work has defined sex-specific alterations in ion channel function in hypothalamic neurons and synaptic transmission in the dorsal striatum, linking cellular physiology to behaviorally relevant circuit output. I am currently working as an assistant research scientist studying estradiol modulation of striatal circuits and plasticity, with a focus on reward-related behaviors and increased susceptibility to neurodegenerative and neuropsychiatric disorders.
Publications: https://loop.frontiersin.org/people/3413444/publications
Professional Experience:
Postdoctoral Research Associate, University of Illinois Urbana-Champaign
Honors & Awards
- American Epilepsy Society (AES) Fellow, 2023
- AES Travel Grant 2023
- PhD scholarship by DAAD-STIBET degree completion grants, University of Muenster, Germany
- CiM-International Max Planck Graduate School Scholarship, University of Muenster, Germany
- NIPER Fellowship, Government of India
Society Memberships
- Society for Neuroscience
- American Epilepsy Society
Joined the College of Engineering: 2024
- Biomedical Engineering